After scoring one run in the season's first 23 innings, the visiting San Francisco Giants scored three times in the top of the sixth Saturday night to defeat the Padres 3-2.

The Giants' victory prevented the Padres from winning three straight games to open a season for only the fourth time in the franchise's 51-season history -- and the first time in 35 seasons.

Steven Duggar opened the San Francisco sixth with a single to center, which turned out to be enough to pin the loss on 22-year-old left-hander Nick Margevicius, who was making his major league debut after pitching only one previous game above Class-A.

With Duggar on first, right-hander Robert Stock replaced Margevicius and immediately moved Duggar to second on a wild pitch before giving up a tie-breaking double to former Padre Yangervis Solarte. Evan Longoria followed with a run-scoring single off Stock, and the Giants scored their third run in the inning on Joe Panik's two-out, bases-loaded single.

The Padres scored two runs in the bottom of the sixth off Giants starter Dereck Rodriguez on a lead-off double by Manuel Margot, a single by Ian Kinsler and a two-run double into the right-field corner by Eric Hosmer off Giants reliever Travis Bergen.

Hosmer represented the tying run at second with no outs. But right-handed Giants reliever Reyes Moronta struck out the side on 12 pitches, getting Manny Machado, Wil Myers and Hunter Renfroe on swinging third strikes.

Margevicius, a seventh-round pick in the 2017 draft out of Rider University, allowed the one run on three hits and no walks with five strikeouts over five-plus innings. He also hit two batters.

Rodriguez got the win, giving up two runs on four hits and no walks with two strikeouts in five-plus innings. Moronta allowed a hit in two scoreless innings with five strikeouts.

Will Smith picked up the first save of the season for the Giants, striking out two in the ninth.

Hosmer had three of the Padres' eight hits. Duggar and Solarte (two doubles) each had two hits for the Giants.

--Field Level Media