Cleveland at Baltimore 6:35 PM ET
The Cleveland Guardians have been clicking lately but that's nothing unusual. Their next opponent is the Baltimore Orioles, who have endured a rare rough patch.
Philadelphia at Detroit 6:40 PM ET
The Philadelphia Phillies' pitching staff possesses the lowest ERA in the major leagues. That's bad news for the usually light-hitting Detroit Tigers, who host the Phillies for a three-game series beginning on Monday night.
Seattle at Tampa Bay 6:50 PM ET
The Seattle Mariners will continue their trek through Florida when they travel up the state's Gulf Coast to open a three-game series Monday night against the Tampa Bay Rays in St. Petersburg, Fla.
Pittsburgh at Cincinnati 7:10 PM ET
The Cincinnati Reds will be trying to avoid a third straight home loss Monday when they open a three-game series against the visiting Pittsburgh Pirates.
Toronto at Boston 7:10 PM ET
The Boston Red Sox look to get the best of an American League East rival for the second straight week, beginning another three-game series against the visiting Toronto Blue Jays, who will head to Fenway Park for the first time this season on Monday.
Atlanta at St. Louis 7:45 PM ET
After pulling out of prolonged slumps that started earlier in the season, the Atlanta Braves and St. Louis Cardinals have become two of the hottest teams in the National League.
LA Dodgers at Chi. White Sox 8:10 PM ET
Garrett Crochet has been one of the few success stories this season for the Chicago White Sox, who begin a three-game series against the visiting Los Angeles Dodgers on Monday.
Miami at Kansas City 8:10 PM ET
The Kansas City Royals will be desperate for offense when they host the Miami Marlins in the opener of their three-game series on Monday night.
Texas at Milwaukee 8:10 PM ET
The Milwaukee Brewers will be looking for another strong outing from ace right-hander Freddy Peralta when they return home to open a three-game series against the Texas Rangers on Monday.
Oakland at LA Angels 9:38 PM ET
Zach Neto is expected to be in the starting lineup Monday when the Los Angeles Angels begin a three-game series against the Oakland A's in Anaheim, Calif.
Washington at San Diego 9:40 PM ET
The first San Diego Padres starter to deliver five straight quality starts this year isn't an obvious choice.
Chi. Cubs at San Francisco 9:45 PM ET
One team coming off a disappointing homestand encounters another glad to be home after a disastrous trip when the Chicago Cubs visit the San Francisco Giants on Monday night to open a four-game series.